28 July 2021: Random Chronic Stress Is a Major Cause of Pancreatic Cancer - abstract

Pancreatic cancer is a major cause of US cancer death. It has risk factors that are preventable, such as cigarette smoking, excess weight, type 2 diabetes, excessive alcohol use and diabetes (Pernick, How Pancreatic Cancer Arises Based on Complexity Theory, 2021). It also has risk factors that are not, such as having blood groups A, B or AB (i.e. not O). This abstract discusses random chronic stress or bad luck, another major cause of pancreatic cancer that is not preventable (Curing Cancer Blog – Part 7 – Random Chronic Stress), which is also a major cause of lung cancer in nonsmokers (Pernick, How Lung Cancer Arises, Based on Complexity Theory, 2021).

 

This subject was discussed in the abstract below, which was not accepted at a recent conference. Although disappointing, the advantage of this rejection is that I can publish it without any restrictions. The full paper is at http://www.natpernick.com/PancreaticcancerFeb2021.html. I welcome your comments to Nat@PathologyOutlines.com.

To continue, see: Random Chronic Stress Is a Major Cause of Pancreatic Cancer - abstract (link), Blog, PDF.

 

How can you help?
 
1. Follow our Curing Cancer Blog at
https://natpernickshealthblog.wordpress.com/ .
2. Sign up for our Curing Cancer Network monthly newsletter by clicking at
https://lp.constantcontactpages.com/su/onz6IND .
3. Become an example to others of anti-cancer behavior. Read our American Code against
Cancer at http://www.natpernick.com/AmericanCodeAgainstCancer.html,
decide what steps you can take to reduce your cancer risk and spread the word through
your social networks.
4. Tell any medical researchers you know about our current grants at
https://www.pathologyoutlines.com/grants.html.
5. Contact me at Nat@PathologyOutlines.com with your suggestions or thoughts on
how you can help.
 

 

 

26 July 2021: Letter to President Joe Biden (July 2021)

 

I emailed this letter earlier this month – to date, there has been no response:

Dear President Biden,

Please identify who I should talk to concerning your goal of “ending cancer as we know it”. To be successful, we need better management, beginning with a strategic plan similar to the one I have developed, see http://www.natpernick.com/StrategicPlanCuringCancer.html.

We need a challenging goal, such as reducing US cancer deaths from the current level of 600,000 per year to 100,000 per year.

We need to identify the knowledge gaps and focus on research to fill them.

We need to abandon outdated concepts, such as talking about “the cure” or “a world without cancer”. We need to stop considering single drugs adequate for treatment. We need to recognize that cancer is within all older adults and that our goal should be to hold it in check, not to eliminate every cancer cell.

We need to study and target systemic networks that nurture malignancy and develop treatments to push cancer cells into networks that are less hazardous.

We need ambitious goals for behavioral changes, such as reducing tobacco use to 5% of the population, excess weight to 10% of the population and ensuring that all Americans get regular medical examinations to detect early disease and to promote prevention.

We need to manage cancer, both within a single patient and in our American society. Focusing solely on technology as the answer is a mistake.

Please review and advise.

Nat Pernick, M.D.

19 July 2021: Video on Strategic plan to substantially reduce cancer deaths

This 3 minute video outlines our strategic plan to substantially reduce cancer deaths.

Strategic plan to substantially reduce cancer deaths

Video summary:

We need a strategic plan to substantially reduce cancer deaths.

• To focus our efforts, identify gaps in knowledge.

• Goal is to reduce annual cancer deaths from current 600K to 100K by 2030.

• It might fail – that may be why others have not attempted this, but I think we can make important progress towards this goal.

Two main aspects – prevention, combinations of treatment.

• Prevention: American Code Against Cancer – not controversial, find ways to better promote these activities (see http://www.natpernick.com/AmericanCod… ).

• Combinations of Treatment: New thesis – If we have 20+ partially effective therapies for a specific type of cancer, then some some subset, in combination, should be substantially effective, see: http://www.natpernick.com/Combination...

• Behavior of whole is greater than sum of behavior of parts.

• Target: primary tumor, also microenvironment, systemic networks.

• Compiling a list, see http://natpernick.com/Pancreatic%20Ca…

• Then start clinical trials, or other means of testing (animal models, cell cultures, computer simulations).

What do you think?

Email me your comments to Nat@PathologyOutlines.com

Links for more information:

Strategic plan (cancer papers are towards the end): http://www.natpernick.com/StrategicPl…

American Code Against Cancer: http://www.natpernick.com/AmericanCod…

Curing Cancer Network newsletter: https://lp.constantcontactpages.com/s...

5 July 2021: Letter to President Biden

 Dear President Biden,

Please identify who I should talk to concerning your goal of “ending cancer as we know it”. To be successful, we need better management, beginning with a strategic plan similar to the one I have developed, see http://www.natpernick.com/StrategicPlanCuringCancer.html.

We need a challenging goal, such as reducing US cancer deaths from the current level of 600,000 per year to 100,000 per year.

We need to identify the knowledge gaps and focus on research to fill them.

We need to abandon outdated concepts, such as talking about “the cure” or “a world without cancer”. We need to stop considering single drugs adequate for treatment. We need to recognize that cancer is within all older adults and that our goal should be to hold it in check, not to eliminate every cancer cell.

We need to study and target systemic networks that nurture malignancy and develop treatments to push cancer cells into networks that are less hazardous.

We need ambitious goals for behavioral changes, such as reducing tobacco use to 5% of the population, excess weight to 10% of the population and ensuring that all Americans get regular medical examinations to detect early disease and to promote prevention.

We need to manage cancer, both within a single patient and in our American society. Focusing solely on technology as the answer is a mistake.

Please review and advise.

5 July 2021: Letter to Director, National Cancer Institute

This is a letter sent to Dr. Norman Sharpless, Director of the US National Cancer Institute, discussing our strategic plan and how substantially reducing cancer deaths is more about management than just finding a technological fix. Email me your comments to Nat@PathologyOutlines.com:

Hi Dr. Sharpless,

 

I read your April 2021 talk to the American Association for Cancer Research (AACR), see

http://www.natpernick.com/AACRSharplessApril2021.pdf, and am distributing it to my

network.

 

In my view, reducing the high number of US cancer deaths is primarily a management

problem to be solved by creating a strategic plan that identifies necessary management and medical / scientific tasks.

 

Rest of article:

 

Link:  http://natpernick.com/SharplessLetterJuly2021.html

Blog: https://natpernickshealthblog.wordpress.com/2021/07/04/letter-to-director-national-cancer-institute

PDF: http://natpernick.com/SharplessLetterJuly2021.pdf

 

 

 

 

4 July 2021: New ideas about cancer

This article lists new or at least not generally accepted ideas about cancer based on my work: Link, Blog, PDF.