Friday, June 25, 2021

23 June 2021: Combinations of therapy to substantially reduce cancer deaths

This essay introduces our strategy of using combinations of therapies directed at all aspects of the malignant process, appropriate for each cancer type, to substantially reduce cancer related deaths. This strategy is based on the understanding that cancer is the result of intersecting webs of biological activity for the cancer cells, their microenvironment and systemic networks affecting the cancer. Effective treatment must damage the end result of these webs sufficiently so that their overall malignant properties cannot continue. This typically cannot be achieved by a single drug.

Entire essay (link), Blog, PDF.

 

 

Friday, June 11, 2021

11 June 2021: What will success look like in the war on cancer?

 

What will success look like in the war on cancer? When we begin with the end in mind, it
helps us focus on what we want to achieve, understand better how this success can be
attained and create processes to do so. The goal of our strategic plan is to reduce US
cancer deaths from the present 600,000 per year to 100,000 per year by 2030. But how will
this happen?
 
Rest of article: PDF, HTML, Blog.
 
How can you help?
 
1. Follow our Curing Cancer Blog at
2. Sign up for our Curing Cancer Network monthly newsletter by clicking at
3. Become an example to others of anti-cancer behavior. Read our American Code against
decide what steps you can take to reduce your cancer risk and spread the word through
your social networks.
4. Tell any medical researchers you know about our current grants at
5. Contact me at Nat@PathologyOutlines.com with your suggestions or thoughts on
how you can help 

Tuesday, June 1, 2021

1 June 2021: The importance of systemic networks in cancer treatment

 

Cancer is a systemic disease. This means it is important to treat not just the obvious tumor
mass but also the systemic cellular networks that nurture the tumor. Surprisingly, most
cancer treatment plans ignore the systemic networks.
 
Targeting systemic tumor networks will be difficult, requiring combinations of combinations of
therapy. We will need different therapeutic strategies for the primary tumor and many of the
systemic networks. Each type of therapy may need to consist of combinations of treatments
to block a sufficient number of steps in the web-like pathways that exist for each cellular
function.
 
This subject was discussed in the abstract below, which was not accepted at a recent
conference. Although disappointing, the advantage of this rejection is that I can publish it
now without any copyright restrictions. The full paper is at
 
Rest of article - PDF, HTML, Blog
 
How can you help?
 
1. Follow our Curing Cancer Blog at
2. Sign up for our Curing Cancer Network monthly newsletter by clicking at
3. Become an example to others of anti-cancer behavior. Read our American Code against
decide what steps you can take to reduce your cancer risk and spread the word through
your social networks.
4. Tell any medical researchers you know about our current grants at
5. Contact me at Nat@PathologyOutlines.com with your suggestions or thoughts on
how you can help